Table 4

Hepatic lipids of guinea pigs treated with 0.0, 0.8, 3.7, and 13.4 mg/kg/day ASBT inhibitor

TreatmentHepatic Lipid
TCFCECTG
mg/kg/day mg/g
ASBT inhibitor
0.0 (control)3.2 ± 1.02.3 ± 0.70.91 ± 0.5532.9 ± 14.7
0.82.9 ± 1.42.4 ± 1.10.52 ± 0.474-160 24.5 ± 7.1
3.73.2 ± 1.02.8 ± 0.90.40 ± 0.324-160 39.8 ± 13.5
13.42.2 ± 0.81.9 ± 0.70.27 ± 0.224-160 26.3 ± 9.5

Data are presented as means ± SD; n = 10/group. Values in the same column with different superscripts are significantly different as determined by one-way ANOVA and the Newman-Keuls as post hoc test.

  • TC, total cholesterol; FC, free cholesterol; EC, esterified cholesterol.

  • 4-160P < 0.01.