Dose | Total Score | Stomach | Cecum |
---|---|---|---|
i.p. study | |||
Saline | 13.25 ± 0.71 | 2.8 ± 0.32 | 5.85 ± 0.36 |
Antisense control | 13.20 ± 0.8 | 2 ± 0.63 | 5.6 ± 0.4 |
0.5 mg/kg | 9.3 ± 0.62cd | 1.9 ± 0.32 | 4.65 ± 0.272-a |
1 mg/kg | 9.85 ± 0.5cd | 1.85 ± 0.46 | 4.6 ± 0.232-a |
5 mg/kg | 10.68 ± 0.51cd | 2.22 ± 0.25 | 4.72 ± 0.422-a |
Rectal study | |||
Antisense control | 15.4 ± 0.4 | 3.4 ± 0.24 | 6.1 ± 0.24 |
0.5 mg/kg | 13 ± 0.172-d | 3 ± 0.01 | 5.2 ± 0.222-b |
1 mg/kg | 11.8 ± 0.282-d | 2.2 ± 0.162-d | 5.4 ± 0.22-b |
5 mg/kg | 12.9 ± 0.332-d | 3.4 ± 0.16 | 5.5 ± 0.17 |