Groups | |||||
---|---|---|---|---|---|
IC | EC | UW | ICPEG50 | ICEG30 | |
Reperfusion | |||||
Cell detachment | 4.0 ± 0.1 | 3.8 ± 0.1 | 3.7 ± 0.1 | 3.7 ± 0.1 | 2.5 ± 0.21-150 |
Tubular necrosis | 4.0 ± 0.2 | 3.8 ± 0.1 | 3.6 ± 0.2 | 3.6 ± 0.1 | 2.5 ± 0.21-150 |
Crest reduction | 4.0 ± 0.1 | 3.8 ± 0.1 | 3.3 ± 0.2 | 3.2 ± 0.1 | 2.7 ± 0.21-150 |
Membrane damage | 4.0 ± 0.1 | 3.5 ± 0.1 | 3.3 ± 0.2 | 3.3 ± 0.1 | 2.5 ± 0.21-150 |
Day 7 or sacrifice day | |||||
Cell detachment | 4.0 ± 0.1 | 3.6 ± 0.1 | 3.3 ± 0.1 | 3.2 ± 0.1 | 2.2 ± 0.11-150 |
Tubular necrosis | 4.0 ± 0.1 | 3.5 ± 0.1 | 3.3 ± 0.1 | 3.2 ± 0.1 | 2.2 ± 0.21-150 |
Crest reduction | 4.0 ± 0.2 | 3.0 ± 0.1 | 3.1 ± 0.1 | 3.0 ± 0.1 | 2.2 ± 0.21-150 |
Membrane damage | 4.0 ± 0.1 | 3.0 ± 0.1 | 3.0 ± 0.1 | 3.0 ± 0.1 | 2.0 ± 0.21-150 |
Day 14 | |||||
Cell detachment | 3.5 ± 0.1 | 3.0 ± 0.1 | 3.0 ± 0.1 | 2.0 ± 0.21-150 | |
Tubular necrosis | 3.3 ± 0.1 | 2.7 ± 0.1 | 2.7 ± 0.1 | 2.0 ± 0.31-150 | |
Crest reduction | 3.0 ± 0.1 | 2.8 ± 0.1 | 2.8 ± 0.1 | 1.7 ± 0.21-150 | |
Membrane damage | 2.8 ± 0.1 | 2.8 ± 0.1 | 2.8 ± 0.1 | 1.6 ± 0.21-150 |
The degree of histological lesioning was determined using a semiquantitative graded scale. 0, no abnormality; 1, mild lesions affecting less than 25% of kidney samples; 2, lesions affecting 25 to 50% of kidney samples; 3, lesions affecting 50 to 75% of kidney samples; 4, lesions affecting over 75% of kidney samples.
↵1-150 P < 0.05 ICPEG30 versus EC, UW, or ICPEG50.