Table 2

Stimulation of cAMP production in CHO cells expressing either the 5-HT4(b) or 5-HT4(e) splice variant of the human 5-HT4 receptor

5-HT4(b)5-HT4(e)
EC50Maximal EffectEC50Maximal Effect
nM nM
5-HT281.000.81.00
SL65.01552440.48290.43