Treatment | Dose | Vehicle II3-a | n | Dexamethasone3-b | n |
---|---|---|---|---|---|
μg kg−1 | |||||
Vehicle I3-c | 13.3 ± 1.3 | 4 | 12.5 ± 1.6 | 5 | |
APNEA | 10 | 227 ± 17 | 5 | 154 ± 293-150 | 5 |
APNEA | 30 | 594 ± 32 | 524 ± 58 | ||
Compound 48/80 | 100 | 1047 ± 30 | 5 | 828 ± 543-150 | 5 |
Compound 48/80 | 300 | 1455 ± 220 | 1296 ± 79 |
Values are mean concentrations in nanograms per milliliter (means ± S.E.M.) of the number of experiments (n) indicated.
↵3-150 p < 0.05 indicates that the value is significantly different from the equivalent value in the vehicle II-treated group (Student's t test).
↵3-a Vehicle for dexamethasone.
↵3-b Dexamethasone, 1 mg kg−1, given i.p. 24 h prior to vehicle I, APNEA, or compound 48/80.
↵3-c Vehicle for APNEA and compound 48/80.