Compounds | Km | Vmax | Vmax/Km |
---|---|---|---|
μM | pmol/min/mg protein | ||
Metformin | 377 ± 38 | 1386 ± 101 | 3.68 ± 0.46 |
Buformin | 48.8 ± 6.9 | 282 ± 25 | 5.78 ± 0.96 |
Phenformin | 15.6 ± 1.1 | 150 ± 7 | 9.62 ± 0.81 |
Km and Vmax values were determined by nonlinear regression analysis. Data are shown as mean ± S.E. (n = 3).