Table 3

Effect of AOAA on the cisplatin protection by MSeCys in R1J cells

TreatmentViability3-aROS3-b
%
Cisplatin25  ± 0.6100  ± 5.2
Cisplatin + 50 μM MSeCys42  ± 2.39  ± 0.9
Cisplatin + 50 μM MSeCys + AOAA25  ± 0.5100  ± 7.7

Experiments were performed as described under Materials and Methods. Results are presented as mean value ± S.D. for four preparations.

  • ↵3-a  Percentage of untreated control; MTT assay; 25 μM cisplatin.

  • ↵3-b  Percentage of cisplatin-treated control; 50 μM cisplatin.