Table 1

Evidence for multidrug-resistant transporters in the human placenta

TransporterLocationReference(s)
MDR1 or P-glycoproteinTrophoblasts; trophoblastic cell line Mylona et al., 1996; Nakamura et al., 1997; Allikmets et al., 1998; Utoguchi et al., 2000
MRP1 and MRP2Syncytiotrophoblast; trophoblastic cell line St-Pierre et al., 2000;Pascolo et al., 2001
MRP1 and MRP3 (expression only)Blood vessel endothelia St-Pierre et al., 2000
MRP5 (expression only)Trophoblastic cell line Pascolo et al., 2001