Concentration | %Control Uptake ± S.D. |
---|---|
μM | |
0 | 100 |
0.01 | 105 ± 7.1 |
0.10 | 119 ± 8.0 |
1.0 | 116 ± 4.5 |
10.0 | 91 ± 0.01 |
Synaptosomes were incubated with 15 nM [3H]DA for 30 min. Control uptake was 160 fmol/mg protein. No significant differences were detected at any concentration of (+)-pentazocine compared with control.N = 2, performed in triplicates.