Specific [3H]DAMGO Binding
| Intestinal Region | Myenteric Plexus | Submucosal Plexus | ||
|---|---|---|---|---|
| Bmax | KD | Bmax | KD | |
| fmol/mg | nM | fmol/mg | nM | |
| Jejunum | 2.898 (1.292–4.503)4-a | 1.477 (−1.089–4.043) | 6.105 (1.504–10.70) | 1.837 (−2.556–6.230) |
| Ileum | 3.181 (0.8803–5.482) | 4.131 (−2.883–11.14) | 6.758 (3.752–9.763) | 1.557 (−0.6417–3.756) |
| Cecum | 6.151 (3.807–8.575) | 1.715 (−0.4195–3.850) | 6.188 (1.592–10.78) | 4.739 (−3.367–12.84) |
| Proximal colon | N.A. | >1000 | 18.33 (7.376–29.29) | 4.105 (−1.651–9.860) |
| Distal colon | N.A. | >1000 | N.D. | N.D. |
N.A., not applicable; N.D., not determined.
↵4-a Values represent mean (95% CI) of 3 to 11 replications using membranes obtained from three to six pigs.