Effect of methamphetamine on t-MeHA levels in caudate putamen and nucleus accumbens
| Time after Treatment | t-MeHA Levels (ng/g) | |
|---|---|---|
| Caudate Putamen | Nucleus Accumbens | |
| Controls | 86 ± 17 | 182 ± 11 |
| t = 30 min | 108 ± 10 (+25%) | 219 ± 10 (+21%) |
| t = 3 h | 151 ± 213-150 (+75%) | 329 ± 293-150 (+81%) |
Mice received methamphetamine (2 mg/kg, i.p.) and were sacrificed 30 min or 3 h after administration of the drug. Percentage of changes compared with controls are indicated between parentheses. Values are means ± S.E.M. of data from five to eight animals.
↵3-150 p < 0.01 vs. corresponding controls in Mann-Whitney test.