IκB-α Abundance EC50 | IκB-α Phosphorylation | ||
---|---|---|---|
EC50 | IC50 | ||
μM | μM | ||
8-Methoxymethyl-IBMX | 27.31 ± 1.25 | 2.01 ± 0.18 | |
Amrinone | 49.10 ± 2.58 | 46.44 ± 3.25 | |
Rolipram | >100 | 93.15 ± 5.07 | |
MBMQ | >100 | ||
Zaprinast | >100 | 76.01 ± 3.62 | |
Pentoxifylline | >100 |
Data are presented as mean ± S.E.M. of three to five independent experiments run in duplicate. EC50/IC50 were determined from the positive and negative slopes of the corresponding curves, respectively.