Binding affinities of neurotensin receptor ligands for cloned mouse NT receptors
| Compound | Ki1-a | |
|---|---|---|
| mNTR1 | mNTR2 | |
| nM | ||
| Neurotensin | 0.25 ± 0.15 | 7.0 ± 1.0 |
| NT-2 | 0.11 ± 0.05 | 3.8 ± 0.3 |
| Levocabastine | >10,000 | 17 ± 2 |
↵1-a IC50 values are the mean of three determinations ± S.E.M. and were calculated using GraphPad Prism software. K i values were then calculated for the individual sites by using the equationK i = IC50/[1 + c/K d).