Activity of ApnA on human P2Y1 and P2Y2receptors expressed in 1321 astrocytoma cells
| EC50(μM) (pD2) | ||
|---|---|---|
| Compound | P2Y1receptor | P2Y2 receptor |
| Ap2A | 5.67 (5.24) | N.A. |
| Ap3A | 0.009 (8.05) | 19.6 (4.70) |
| Ap4A | 0.16 (6.77) | 0.093 (7.03) |
| Ap5A | 1.66 (5.77) | 2.64 (5.57) |
| Ap6A | 1.77 (5.75) | 5.18 (5.28) |
EC50 and pD2 values for intracellular calcium mobilization for ApnA on human P2Y1 and P2Y2receptors expressed in 1321 astrocytoma cells (n = 3).
N.A., not applicable.