Table 3

PA2 values of CTAP (i.t.) against DAMGO and DPDPE (i.t.) in placebo-treated mice

StrainPA2 of CTAP, log M
DAMGODPDPE
H-ND410.6 (−1.35)11.2 (−0.75)
CR-SW11.1 (−1.06)11.0 (−0.92)

Procedures for pellet implantation, administering DAMGO or DPDPE i.t., and measuring antinociception are given under Materials and Methods. Slopes of pA2 are given in parentheses.