Pretreatment | Mortality | |
---|---|---|
Saline | Cisplatin | |
No. dead mice/total | ||
Saline | 0 /8 | 6 /111-a |
Acivicin | 0 /8 | 0 /8 |
AOAA | 0 /7 | 0 /7 |
Mice were pretreated with saline, acivicin, or AOAA followed by an injection of either saline or 15 mg/kg cisplatin. The mice were monitored for 5 days. The acute mortality of the treatment was determined by the number of mice that died within 5 days.
↵1-a  Significantly different from all other groups p < 0.04.