Table 1

CCK antagonist binding

AdditionNCI-H209 CellsNCI-H345 Cells
CI-9885  ± 0.54  ± 1
L-365,2602  ± 0.23  ± 0.5
L-364,718200  ± 30250  ± 40

The mean IC50 (nM) ± S.D. of four determinations, each performed in duplicate to inhibit specific 125I-CCK-8 binding, is indicated.