Mean ED50 values in milligrams per kilogram (±95% confidence limits) and dose ratios for SNC162, morphine, or U-50,488 after acute pretreatment with saline or 10.0 mg/kg SNC80
↵2-150 95% confidence limits after SNC80 treatment do not overlap with 95% confidence limits after saline treatment.
↵2-a The highest dose tested (32.0 mg/kg SNC162) did not decrease rates of responding to ≤50% in one monkey. For analysis, an ED50 value of 32.0 mg/kg was assigned for this monkey.