Kinetic parameters for chlorzoxazone 6-hydroxylation
| Treatment | Km | pValue | Vmax | p Value |
|---|---|---|---|---|
| μM | ||||
| Saline | 150 ± 21 | 0.100 | 1.18 ± 0.23 | 0.001 |
| Ethanol (3.0 g/kg) | 221 ± 65 | 2.27 ± 0.12 | ||
| Saline | 109 ± 22 | 0.250 | 1.32 ± 0.55 | 0.005 |
| Nicotine (1.0 mg/kg) | 131 ± 17 | 2.35 ± 0.04 |
Mean ± S.D., n = 4 animals.