Table 1

Ethanol sleep time and acute functional tolerance (rotarod test) do not differ between control and GIRK2 null mutant (−/−) mice

ParameterControl MiceMutant Mice
MalesFemalesMales (−/−)Females (−/−)
Sleep time (min)81.9  ± 11.671.2  ± 9.076.5  ± 9.971.9  ± 13.9
n  = 11 n  = 11 n  = 11 n  = 12
BEC at RORR (mg/ml)4.41  ± 0.164.24  ± 0.124.13  ± 0.134.48  ± 0.16
n  = 11 n  = 11 n  = 11 n  = 12
BEC1 in AFT (mg/ml)2.38  ± 0.082.40  ± 0.092.12  ± 0.072.36  ± 0.06
n  = 14 n  = 15 n  = 14 n  = 16
BEC1 − BEC1–2 in AFT (mg/ml)1.28  ± 0.081.16  ± 0.091.39  ± 0.201.35  ± 0.11
n  = 14 n  = 15 n  = 14 n  = 16

Values are means ± S.E.M.

  • n, number of animals; AFT, acute functional tolerance; RORR, return of righting response.