Effect of CAM on the development of pneumonia in influenza virus-infected mice
| Days after Infection | Percentage of Area of Pneumonia (mean ± S.E.)/CAM | ||
|---|---|---|---|
| 0 mg/day | 2 mg/day | 20 mg/day | |
| 3 | 36.0 ± 8.5 | 26.1 ± 3.9 | 19.0 ± 4.8 |
| 5 | 41.3 ± 8.0 | 42.6 ± 11.0 | 19.3 ± 3.81-a |
Mice were intranasally infected with influenza virus, and CAM at 0, 2, or 20 mg/day was orally administered. Lungs were removed from four to six mice in each group on days 3 and 5, and the percentage of area of pneumonia in each lung was determined as described in the text.
↵1-a Significant difference (p < 0.05) vs. control by one-way ANOVA and post hoc Dunnett's test.