Table 2

Effect of DX treatment on the transcript levels of cytokines and COXs in colonic tissues

Control (n = 4)Group A (n = 5)Group B (n = 6)Group C (n = 6)Group D (n = 7)Group E (n = 7)
TNF-α0.10  ± 0.030.65  ± 0.050.58  ± 0.060.40  ± 0.052-a 0.30  ± 0.052-a 0.15  ± 0.062-a 2-b
IL-1β0.11  ± 0.020.43  ± 0.060.40  ± 0.070.35  ± 0.030.22  ± 0.032-a 0.18  ± 0.022-a
IFN-γ0.12  ± 0.050.52  ± 0.120.56  ± 0.080.38  ± 0.042-a 0.29  ± 0.052-a 0.12  ± 0.052-a 2-b
COX-10.90  ± 0.120.96  ± 0.100.93  ± 0.100.85  ± 0.080.92  ± 0.100.88  ± 0.11
COX-20.10  ± 0.020.85  ± 0.120.82  ± 0.100.42  ± 0.102-a 0.35  ± 0.112-a 0.12  ± 0.022-a 2-b

Amounts of cytokine and COX transcripts are expressed as relative concentrations of β-actin. Results are means ± S.E.

  • 2-a  P < 0.05, compared with groups A and B.

  • 2-b  P < 0.05, compared with groups C and D.