The ED50 values of β-endorphin, DAGO, DADLE, deltorphin II, and DPDPE given either i.c.v. or i.c. on the ethanol ulcer model in the rat
| Compounds | ED50 (95% Confidence Limits) | ED50 i.c.v./ED50 i.c. | |
|---|---|---|---|
| i.c.v. | i.c. | ||
| pmol/rat | |||
| β-Endorphin | 3.5 | 0.8 | 4.37 |
| (1.66–7.35) | (0.62–1.024) | ||
| DAGO | 6.8 | 9.0 | 0.75 |
| (2.26–20.4) | (2.4–33) | ||
| DADLE | 75.0 | 45.0 | 1.50 |
| (36–144) | (16–126) | ||
| Deltorphin II | 120.0 | 0.25 | 545.0 |
| (40–360) | (0.08–0.775) | ||
| DPDPE | 1100 | 7.0 | 157.0 |
| (458–2640) | (1.66–29.4) | ||