Table 5

Relative binding affinity and potency at μ-opioid receptor, NE uptake, and intrathecal potency

MORDALDA[Dmt1]DALDATramadol5-150
μ-Opioid binding affinity10.670.001
Potency in GPI assay10.121
Inhibition of NE uptake1162121000
Intrathecal potency11431600.2

  • ↵5-150  Derived from Codd et al. (1995).