Comparison of mean blood gases, O2 content, hemoglobin, and hematocrit
| Parameter | DCLHb Group (n = 16) | Control Group (n = 16) | ||
|---|---|---|---|---|
| Baseline | CPR | Baseline | CPR | |
| pH (A) | 7.40 ± 0.03 | 7.44 ± 0.18 | 7.41 ± 0.03 | 7.41 ± 0.15 |
| pH (V) | 7.37 ± 0.04 | 7.28 ± 0.08 | 7.39 ± 0.05 | 7.19 ± 0.24 |
| pH (IJ) | 7.37 ± 0.03 | 7.29 ± 0.10 | 7.38 ± 0.04 | 7.30 ± 0.17 |
| pCO2 (A) | 41.56 ± 2.94 | 38.00 ± 12.76 | 41.31 ± 2.80 | 39.75 ± 13.67 |
| pCO2 (V) | 45.44 ± 4.99 | 62.75 ± 14.76 | 44.88 ± 6.64 | 74.86 ± 28.50 |
| pCO2(IJ) | 47.00 ± 5.14 | 61.63 ± 14.41 | 47.06 ± 6.72 | 72.79 ± 32.55 |
| O2 sat (A) | 94.39 ± 2.69 | 81.78 ± 11.16 | 93.32 ± 3.34 | 80.94 ± 13.60 |
| O2 sat (V) | 76.56 ± 1.90 | 31.03 ± 16.01 | 72.54 ± 16.94 | 21.52 ± 10.97 |
| O2 sat (IJ) | 76.58 ± 15.21 | 34.93 ± 14.30 | 73.81 ± 15.71 | 30.36 ± 16.43 |
| pO2 (A) | 98.75 ± 16.61 | 67.14 ± 21.89 | 92.94 ± 19.97 | 65.33 ± 15.22 |
| pO2 (V) | 59.56 ± 18.01 | 30.56 ± 8.172-150 | 53.44 ± 11.58 | 26.64 ± 5.14 |
| pO2 (IJ) | 60.38 ± 15.28 | 32.06 ± 6.55 | 56.00 ± 13.31 | 29.40 ± 4.31 |
| O2content (A) | 12.33 ± 1.47 | 12.83 ± 1.67 | 12.20 ± 1.09 | 11.93 ± 1.39 |
| O2 content (V) | 9.75 ± 1.98 | 4.45 ± 2.202-150 | 8.50 ± 2.48 | 2.50 ± 1.31 |
| O2 content (IJ) | 9.29 ± 2.17 | 5.17 ± 2.072-150 | 9.46 ± 1.74 | 3.23 ± 1.51 |
| EXs O2 | 0.10 ± 0.143 | 0.47 ± 0.152-160 | 0.26 ± 0.26 | 0.72 ± 0.20 |
| EXc O2 | 0.13 ± 0.13 | 0.44 ± 0.16 | 0.14 ± 0.11 | 0.55 ± 0.15 |
| Hemoglobin (A) | 9.29 ± 1.37 | 10.44 ± 1.082-150 | 9.36 ± 0.83 | 9.78 ± 0.98 |
| Hematocrit (A) | 0.33 ± 0.04 | 0.30 ± 0.04 | 0.33 ± 0.03 | 0.32 ± 0.03 |
| Hematocrit (V) | 0.33 ± 0.02 | 0.30 ± 0.04 | 0.31 ± 0.03 | 0.31 ± 0.03 |
| Hematocrit (IJ) | 0.31 ± 0.04 | 0.30 ± 0.04 | 0.33 ± 0.03 | 0.30 ± 0.06 |
| Lactate (A) | 2.07 ± 0.34 | 5.23 ± 1.652-150 | 1.97 ± 0.38 | 6.48 ± 1.30 |
| Lactate (V) | 2.31 ± 0.43 | 5.94 ± 1.41 | 2.13 ± 0.43 | 7.18 ± 1.41 |
| Lactate (IJ) | 2.29 ± 0.42 | 6.02 ± 1.41 | 2.16 ± 0.39 | 7.19 ± 1.36 |
O2 content is expressed in milliliters per deciliter (calculated as [(PO2 × 0.003) + (1.34 × O2sat × hemoglobin)] × 1/100). Other units are as follows: hemoglobin, grams per deciliter; lactate, millimoles per liter; PCO2 and PO2, torrs; and O2 sat, percent.
A, aortic; V, ventricular; IJ, internal jugular; EXs O2, systemic oxygen extraction is defined by ((aortic − venous) × oxygen content)/aortic oxygen content; EXc O2, cerebral oxygen extraction is defined by ((aortic − internal jugular) × oxygen content)/aortic oxygen content; sat, saturation.
↵2-150 p < 0.05 at same time points (DCLHb group vs. saline control group).
↵2-160 p < 0.001 at same time points (DCLHb group vs. saline control group).