Table 4

Levels of CB1 receptor protein in Δ9-THC-treated, morphine-treated, and combination-treated mice

TreatmentMidbrain Int. Vol.Spinal Cord Int. Vol.
VehicleDrugVehicleDrug
Δ9-THC3.2  ± 0.694-a 5.1  ± 0.793.6  ± 0.304.2  ± 0.33
Morphine2.5  ± 0.421.6  ± 0.121.7  ± 0.432.2  ± 0.72
Δ9-THC + morphine1.4  ± 0.481.6  ± 0.090.34  ± 0.090.89  ± 0.064-150

Western blots were quantified using phosphorimaging, and an average of the four trials was taken.

  • Int. Vol., integrated volume.

  • ↵4-a All integrated volumes are presented as table value × 105.

  • ↵4-150  Significantly different from vehicle-treated, nontolerant control.p < 0.05, by Student's t test.