Treatment | Midbrain O.D. | Spinal Cord O.D. | ||
---|---|---|---|---|
Vehicle | Drug | Vehicle | Drug | |
Δ9-THC | 0.27 ± 0.05 | 0.34 ± 0.05 | 0.30 ± 0.03 | 0.32 ± 0.02 |
Morphine | 0.47 ± 0.04 | 0.13 ± 0.032-150 | 0.41 ± 0.05 | 0.45 ± 0.05 |
Δ9-THC +morphine | 0.42 ± 0.07 | 0.46 ± 0.06 | 0.22 ± 0.04 | 0.55 ± 0.082-150 |
Western blots were quantified using scanning densitometry, and an average of the four trials was taken.
↵2-150 Significantly different from vehicle-treated, nontolerant control. p < 0.05, by Student's t test.