Levels of μ-receptor protein in Δ9-THC-treated, morphine-treated, and combination-treated mice
| Treatment | Midbrain O.D. | Spinal Cord O.D. | ||
|---|---|---|---|---|
| Vehicle | Drug | Vehicle | Drug | |
| Δ9-THC | 0.35 ± 0.02 | 0.37 ± 0.02 | 0.20 ± 0.02 | 0.28 ± 0.03 |
| Morphine | 0.36 ± 0.03 | 0.19 ± 0.031-150 | 0.12 ± 0.01 | 0.13 ± 0.04 |
| Δ9-THC +morphine | 0.56 ± 0.02 | 0.54 ± 0.04 | 0.14 ± 0.01 | 0.23 ± 0.031-150 |
Western blots were quantified using scanning densitometry, and an average of the four trials was taken.
↵1-150 Significantly different from vehicle-treated, nontolerant control. p < 0.05, by Student's t test.