Effects of varying the timing of Cereport and [14C]carboplatin infusions on delivery of [14C]carboplatin to peripheral tumors
| Group | Timing of Cereport and Carboplatin Infusions | ||
|---|---|---|---|
| Carboplatin 2 min before Cereport | Simultaneous | Carboplatin 2 min after Cereport | |
| Saline | 73.1 (9.3) | 89.6 (8.6) | 87.6 (8.6) |
| Cereport (0.1) | 297.2 (52.2)3-160 | 226.0 (38.5)3-160 | 221.0 (43.5)3-160 |
| Cereport (0.5) | 148.7 (20.9)3-160 | 168.2 (21.5)3-160 | 77.8 (10.9) |
N for all groups is 10 to 11. Data presented as mean nanocuries per gram of tissue ± S.E.M.
↵3-160 p < 0.01 vs. saline.