Table 4
In vivo pharmacodynamics of ISIS 22023 in hepatocyte
Parameter
Estimate ± S.E.
E
max
(% control)
140.0 ± 62.7
EC
50
(μg in hepatocyte/g liver)
16.1 ± 9.29
E
0
(% control)
26.0 ± 12.0
n
3.97 ± 4.06