Drug | Effect | df | Horizontal Activity | Vertical Activity | ||
---|---|---|---|---|---|---|

F Value | P Value | FValue | P Value | |||

Caffeine | Main |
F
_{2,80}
| 6.138 | .008 | 5.003 | .017 |

Interaction |
F
_{8,80}
| 3.995 | <.001 | 2.385 | .023 | |

Nicotine | Main |
F
_{2,80}
| 4.269 | .029 | 3.626 | .045 |

Interaction |
F
_{8,80}
| 0.179 | .981 | 0.382 | .888 | |

Amphetamine | Main |
F
_{2,80}
| 3.494 | .049 | 0.718 | .500 |

Interaction |
F
_{8,80}
| 3.333 | .002 | 1.358 | .227 | |

Cocaine | Main |
F
_{2,80}
| 0.771 | .475 | 1.208 | .319 |

Interaction |
F
_{8,80}
| 2.311 | .044 | 1.475 | .201 |

Shown are the *F* values, degrees of freedom (df), and significance levels of difference (*P* values) revealed by ANOVA. Two-way repeated measures ANOVA on one repeated factor was used to depict quantitative (main effect) and qualitative (interaction) differences in the effects of drugs on the two measures of ambulatory activity in water, 0.25-CAFF, and 1.0-CAFF groups. The dose-response functions are plotted in Figs. 1 and 2.