Table 2

Comparison of microsomal OP 5-hydroxylation at a low substrate concentration (4 μM) in liver samples of genotyped Chinese from two ethnic groups, Han and Zhuang

CYP2C19 GenotypeHan (n)Zhuang (n)Total Samples (n)
wt/wt 188  ± 632-a (9)125  ± 562-150 (10)155  ± 64 (19)
wt/m1 107  ± 542-151 (6)97  ± 59 (6)102  ± 522-151 (12)
m1/m1 20  ± 282-152 (2)26 (1)22  ± 202-152 (3)
wt/wt + wt/m1 + m1/m1 140  ± 79 (17)109  ± 56 (17)124  ± 69 (34)
  • n, number of samples examined.

  • 2-a  Data represent mean ± S.D.

  • 2-150  Different from Han ethnic group (P < .05).

  • 2-151  Different from wt/wt(P < .05).

  • 2-152  Different from wt/wt andwt/m1 (P < .05).