Agonist potencies and maximum responses in canine subcutaneous resistance arteries
| Agonist | pEC50 ± S.E. (n) | Maximum (%) ± S.E. (n) |
|---|---|---|
| NE | 6.41 ± 0.1 (8) | 114.9 ± 2.48 (8) |
| (R)-A-61603 | 7.88 ± 0.1 (6) | 106.4 ± 4.52 (6) |
| PE | 5.83 ± 0.1 (10) | 99.82 ± 11.3 (10) |
| UK14304 | 7.29 ± 0.22 (3) | 42.33 ± 11.3 (3) |
Potencies and maximal responses for NE, (R)-A-61603, PE, and UK14304 in canine subcutaneous resistance artery. Maximum responses are expressed as a percentage of an initial contraction to 10 μM NE.n represents the number of experiments. The weak and inconsistent response to UK14304 cannot entirely exclude α2-adrenoceptor involvement.