Test drug | Dose (mg/70 kg) | Placebo | Opioid | Barbiturate/ Benzodiazepine | Other |
---|---|---|---|---|---|
% | |||||
Hydromorphone | 0 | 100 | |||
0.125 | 100 | ||||
0.25 | 84 | 16 | |||
0.5 | 63 | 38 | |||
1 | 38 | 59 | 3 | ||
2 | 38 | 63 | |||
3 | 16 | 84 | |||
4 | 100 | ||||
Pentazocine | 0 | 100 | |||
4 | 94 | 6 | |||
8 | 97 | 3 | |||
16 | 59 | 41 | |||
32 | 25 | 69 | 6 | ||
64 | 31 | 38 | 19 | 13 | |
Butorphanol | 0 | 100 | |||
0.375 | 78 | 9 | 13 | ||
0.75 | 72 | 16 | 13 | ||
1.5 | 28 | 38 | 28 | 6 | |
3.0 | 13 | 56 | 31 | ||
6.0 | 13 | 41 | 34 | 13 | |
Nalbuphine | 0 | 88 | 13 | ||
1.5 | 75 | 25 | |||
3 | 50 | 50 | |||
6 | 53 | 47 | |||
12 | 38 | 38 | 25 | ||
24 | 13 | 63 | 25 | ||
Buprenorphine | 0 | 100 | |||
0.055 | 84 | 3 | 13 | ||
0.11 | 97 | 3 | |||
0.22 | 66 | 34 | |||
0.45 | 19 | 81 | |||
0.9 | 9 | 91 |
Percentage of identifications of each test drug dose out of 32 responses (four responses for each of eight subjects). Identifications as phenothiazines, stimulants, phencyclidine, and hallucinogens were combined and listed as Other. Not all rows add to 100% due to rounding.