Effect of SB-277011-A on apomorphine-induced climbing
| Treatment | Cumulative Climbing Score |
|---|---|
| Vehicle/saline | 42-160 |
| Vehicle/apomorphine | 37 |
| SB-277011-A, 4 mg/kg/apomorphine | 30 |
| SB-277011-A, 9 mg/kg/apomorphine | 35 |
| SB-277011-A, 20 mg/kg/apomorphine | 37 |
| SB-277011-A, 41 mg/kg/apomorphine | 212-160 |
Data are for n = 10 per treatment group with a 4-h pretreatment before apomorphine and tested 10 and 20 min after apomorphine treatment.
↵2-160 P = .001 compared to vehicle/apomorphine by the Mantel-Haenszel General Association test.