Table 1

Agonist actions of BU48 and standard opioids on the electrically induced contractions of the mouse vas deferens and their antagonism by NTI

IC50NTI (Ke)
nM
BU480.2  ± 0.100.11  ± 0.02
DAMGO17.6  ± 2.06.5  ± 1.7
DPDPE0.93  ± 0.040.14  ± 0.03
U6959328.4  ± 3.619.6  ± 2.3

Experiments were performed as described under Materials and Methods. Values represent means ± S.E. from three separate tissues and were determined as described under Materials and Methods.