Plasma, brain, and CSF levels of AR-R 17779 at 30 and 60 min after the administration of a 30 mg/kg i.p. dose. Values are mean ± S.E. The number of animals per group are in parentheses.
| Time | Plasma Conc. | Brain | CSF |
|---|---|---|---|
| min | μM | ||
| 30 | 73.5 ± 13.3 (4) | 4.0 ± 0.5 (4) | 6.6 ± 1.7 (4) |
| 60 | 45.6 ± 7.6 (6) | 2.4 ± 0.3 (6) | 4.2 ± 1.2 (5) |