Agonists effective at reducing the amplitude of sAHP in CA3 hippocampal pyramidal cells
| Agonist | EC501-a | Emax | Slope |
|---|---|---|---|
| −log | % Inhibition | ||
| 5-HT (8) | 5.3 ± 0.11 | 58.2 ± 4.7 | 2.6 ± 0.4 |
| 5-CT (7) | 7.5 ± 0.08 | 71.9 ± 7.5 | 1.6 ± 0.4 |
| 5-MeOT (7) | 4.8 ± 0.12 | 60.2 ± 6.7 | 1.9 ± 0.3 |
Values are mean ± S.E., and the number of cells is shown in parentheses. WAY-100635 (0.1–1.0 μM) and GR-113808 (0.1 μM) were included in the stock buffer.
↵1-a Significant F= 174, P < .001. All comparisons were significantly different.