The effect of propranolol (1 mg/kg) on the loss of ethoxyresorufin dealkylase in the liver and brains of rats given 25 μg LPS by i.c.v. injection
| Treatment | Liver EROD | Liver P450 | Brain EROD |
|---|---|---|---|
| pmol/mg of protein/min | nmol/mg of protein | pmol/mg of protein/min | |
| Saline | 42.6 ± 1.74 | 0.59 ± 0.03 | 1.08 ± 0.08 |
| Saline + propranolol | 39.5 ± 5.35 | 0.53 ± 0.03 | 1.22 ± 0.09 |
| LPS | 24.8 ± 2.363-a | 0.42 ± 0.033-a | 0.91 ± 0.073-a |
| LPS + propranolol | 22.0 ± 4.603-a | 0.41 ± 0.063-a | 0.82 ± 0.093-a |
Each value is the mean ± S.E., n = 4.
↵3-a Significantly different from corresponding control.