Behavioral effects in the defensive withdrawal test following acute treatment with 3.2 mg/kg CP-154,526 (CP 3.2; n = 6), 32 mg/kg CP-154,526 (CP 32; n = 5), or vehicle (n = 4)
| Treatment | Latency | Duration | No. of Entries |
|---|---|---|---|
| s | s | ||
| Vehicle | 173.5 ± 35.0 | 414.8 ± 54.2 | 8.0 ± 0.7 |
| CP 3.2 | 102.7 ± 26.7 | 343.7 ± 65.5 | 7.7 ± 1.0 |
| CP 32 | 64.0 ± 27.7 | 438.7 ± 47.6 | 9.0 ± 1.2 |
The latency of the animals to initially leave the tube (latency), the total time the animals stayed in the tube (duration), and the number of entries into the open field indicates the locomotor activity of the animals. Data are expressed as means ± S.E.