Table 4

Physiological parameters for (0.5 nmol) Con-G and vehicle-treated rats with and without MCAo

Time Point	MABP	HR	pO₂	pCO₂	pH
h	mm Hg	beat/min	mm Hg
Con-G-treated rats, no MCAo
Baseline	95 ± 17	267 ± 26	97 ± 15	31 ± 3	7.45 ± 0.02
1	90 ± 11	236 ± 111	105 ± 17	29 ± 11	7.43 ± 0.02
2.5	109 ± 13	280 ± 75	92 ± 7	30 ± 5	7.41 ± 0.03
4.5	122 ± 18^4-150	316 ± 179	106 ± 26	24 ± 3	7.43 ± 0.04
6.5	125 ± 10^4-150	250 ± 93	82 ± 10	26 ± 1	7.47 ± 0.04
Vehicle-treated rats, 2-h MCAo and reperfusion
Baseline	98 ± 8	282 ± 59	94 ± 13	29 ± 7	7.43 ± 0.03
1	136 ± 10^4-160	349 ± 41	99 ± 21	23 ± 4	7.44 ± 0.03
2.5	132 ± 4^4-150	291 ± 98	87 ± 18	25 ± 9	7.45 ± 0.02
4.5	120 ± 11	349 ± 40	79 ± 3	33 ± 3	7.42 ± 0.04
6.5	102 ± 14	298 ± 88	79 ± 7	33 ± 3	7.42 ± 0.02
Con-G-treated rats, 2-h MCAo and reperfusion
Baseline	95 ± 2	196 ± 55	91 ± 2	32 ± 4	7.48 ± 0.01
1	112 ± 15	256 ± 116	75 ± 4	33 ± 4	7.47 ± 0.04
2.5	101 ± 2	305 ± 100	75 ± 4	33 ± 3	7.43 ± 0.02
4.5	124 ± 23	271 ± 81	83 ± 22	35 ± 6	7.44 ± 0.02
6.5	115 ± 18	314 ± 129	72 ± 9	32 ± 3	7.46 ± 0.03

Injections were given at 30 min and 2, 4, and 6 h after occlusion, and measurements were taken at 30 min after each injection. Values presented as mean ± S.D.

↵4-150 P < .05,
↵4-160 P < .01, compared with baseline value (Dunnett's post hoc test).