Selectivity Factor | Mammals | Insects | Differences |
---|---|---|---|
Potency on nerve | |||
Due to temperature dependence | Low (37°C) | High (25°C) | 5 |
Due to intrinsic sensitivity | Low | High | 10 |
Recovery | Fast | Slow | 5 |
Detoxication rate | |||
Due to enzymatic action | High | Low | 3 |
Due to body size | High | Low | 3 |
Overall difference = 2250 (Song and Narahashi, 1996).