Table 1

Factors contributing to selective toxicity of pyrethroids

Selectivity FactorMammalsInsectsDifferences
Potency on nerve
 Due to temperature dependenceLow (37°C)High (25°C)5
 Due to intrinsic sensitivityLowHigh10
 RecoveryFastSlow5
Detoxication rate
 Due to enzymatic actionHighLow3
 Due to body sizeHighLow3

Overall difference = 2250 (Song and Narahashi, 1996).