Table 4

Individual and time-related differences in the effects of SA cocaine on plasma PRL

RatSA Day 1SA Day 5
Presession PRLCocaine IntakePostsession PRLPresession PRLCocaine IntakePostsession PRL
ng/ml mg/kg ng/ml ng/ml mg/kg ng/ml
T45e1.112.9482.00.01 9.40120.010.08
T65e1.1 3.1274.00.02 3.75118.0 5.69
T51e1.1 3.6938.50.004-a  2.41 55.5 3.18
T29e1.1 5.6666.00.24 2.71104.0 0.80
T49e1.1 4.0130.00.20 6.96114.0 0.54
T47e1.1 3.7027.50.004-a  4.87 73.5 0.004-a
T64e1.1 6.2848.00.0119.63109.0 0.23
T58e1.1 3.42 7.03.7516.12 49.0 0.46
T23e1.1 6.8132.04.7210.60 36.75 0.31
T43e1.1 8.85 3.04.39 4.56  3.0 2.62

Data represent presession and postsession PRL and cocaine intake on days 1 and 5 of SA testing in 10 representative rats.

  • 4-a Plasma PRL was undetectable.