Table 2

Values of coefficient and exponent for power functions relating pharmacokinetic parameters of rPSGL Ig with body weight across different animal species

CLVcVssVzt1/2
ml/h ml h
φ2-a 0.9301.0641.0841.0870.159
α2-a 0.36845.095.7100.2189.6
r 2 2-b 0.940.9880.9880.9850.747
Human pharmacokinetics2-c 19.24138956710143373
  • 2-a φ and α are the parameters for the power functionY = αWφ.

  • 2-b r2 value for the regression analysis of pharmacokinetic parameters versus body weight.

  • 2-c Predicted pharmacokinetic parameters of rPSGL-Ig in humans (70 kg).