Table 1

Summary of the antinociceptive activity of the [TMT¹]DPDPE analogs

Compound Structure	A₅₀	95% Confidence Limit
	nmol
DPDPE	9.77	7.24–13.17
[(2S,3S)-TMT¹]DPDPE	7.05	4.12–12.08
[(2S,3R)-TMT¹]DPDPE	47.23	36.26–61.53
[(2R,3R)-TMT¹]DPDPE	34.5% at 100 nmol	N/A
[(2R,3S)-TMT¹]DPDPE	40.37	28.26–57.67