|
μg/kg/min
|
MABP (mmHg) |
WKY | 122 ± 5 | 123 ± 5 | 122 ± 6 |
P < .05 |
P < .05 |
P < .05 |
SHR | 183 ± 71-b
| 166 ± 71-a
1-b
| 164 ± 61-a
1-b
|
HR (bpm) |
WKY | 394 ± 9 | 405 ± 9 | 425 ± 111-a
|
P = .31 |
P < .05 |
P = .12 |
SHR | 388 ± 8 | 399 ± 5 | 403 ± 61-a
1-b
|
RBF (ml/min/g kid) |
WKY | 9.8 ± 0.4 | 9.7 ± 0.4 | 8.9 ± 0.41-a
|
P = .28 |
P = .54 |
P < .05 |
SHR | 8.0 ± 0.81-b
| 8.6 ± 0.71-b
| 8.8 ± 1.0 |
RVR [mmHg/(ml/min/g kid)] |
WKY | 12.5 ± 0.7 | 12.8 ± 0.4 | 13.9 ± 1.0 |
P < .05 |
P < .05 |
P < .05 |
SHR | 24.0 ± 2.61-b
| 19.6 ± 1.11-a
1-b
| 19.6 ± 1.11-a
1-b
|
GFR (ml/min/g kid) |
WKY | 1.57 ± 0.07 | 1.62 ± 0.09 | 1.64 ± 0.05 |
P = .69 |
P = .21 |
P = .88 |
SHR | 1.48 ± 0.16 | 1.58 ± 0.16 | 1.56 ± 0.14 |
UV (μl/30 min/g kid) |
WKY | 202 ± 22 | 478 ± 671-a
| 559 ± 761-a
|
P = .19 |
P < .05 |
P = .25 |
SHR | 398 ± 771-b
| 638 ± 941-a
1-b
| 604 ± 991-a
|
UNaV (μmol/30 min/g kid) |
WKY | 53.5 ± 17.2 | 137.4 ± 24.01-a
| 168.0 ± 18.81-a
|
P = .42 |
P < .05 |
P = .56 |
SHR | 83.3 ± 17.0 | 166.6 ± 23.31-a
| 169.3 ± 24.41-a
|
UKV (μmol/30 min/g kid) |
WKY | 44.3 ± 2.5 | 36.9 ± 3.4 | 28.2 ± 2.41-a
|
P = .07 |
P < .05 |
P = .77 |
SHR | 59.3 ± 9.21-b
| 52.0 ± 6.61-b
| 39.6 ± 4.61-a
1-b
|