Table 2

Effects of DCUKA on the binding of various radioligands to rat telencephalic membranes

LigandDCUKA IC50LigandDCUKA IC50
μM μM
[3H]CGP39653>200  (19.1  ± 2.1)[3H]flunitrazepam>200  (43.6 ± 2.0)
[3H]Ifenprodil>200  (9.9  ± 3.7)[3H]flumazenil>200  (16.8 ± 4.7)
[3H]Kainate>200  (21.5  ± 5.9)[3H]SR9553183  (68.0 ± 6.9)
[3H]AMPA>200  (21.2  ± 9.4)[3H]rauwolscine>200  (−2.4 ± 15.0)
  • Percentage of displacement obtained in the presence of 200 μM DCUKA is given in parentheses.