Compound | T1/2 on | T1/2off |
---|---|---|
min | ||
NAT (15 μM) | 4.1 ± 0.3 | 34.8 ± 3.8 |
GLY (30 nM) | 4.2 ± 0.4 | 68.1 ± 4.01-a |
REP (10 nM) | 12.3 ± 2.41-a | 175.0 ± 1.01-a |
Time courses were studied at equipotent concentrations of 2× respective IC50s. T1/2 on, time to half-maximal inhibition; T1/2 off, time to half-recovery from maximal inhibition.
↵1-a Significantly different from the values with NAT.