n | pA2 | Slope | α1A | α1B | α1D | ||||
---|---|---|---|---|---|---|---|---|---|
pKi | nH | pKi | nH | pKi | nH | ||||
RS-17053 | 6 | 8.38 ± 0.03 | 0.55 ± 0.05 | 8.59 ± 0.08 | 0.8 ± 0.1 | 7.06 ± 0.09 | 1.1 ± 0.1 | 7.40 ± 0.11 | 1.1 ± 0.1 |
(+)-Niguldipine | 8.59 ± 0.14 | 0.8 ± 0.1 | 6.57 ± 0.10 | 0.8 ± 0.1 | 6.61 ± 0.11 | 1.0 ± 0.1 | |||
5-MU | 12 | 8.25 ± 0.18 | 0.75 ± 0.05 | 8.24 ± 0.11 | 0.8 ± 0.1 | 6.40 ± 0.13 | 0.7 ± 0.1 | 6.76 ± 0.14 | 0.8 ± 0.1 |
WB4101 | 8 | 8.42 ± 0.16 | 0.49 ± 0.05 | 9.28 ± 0.13 | 0.7 ± 0.1 | 7.29 ± 0.17 | 0.8 ± 0.1 | 8.42 ± 0.08 | 0.5 ± 0.1 |
BMY7378 | 8 | 6.80 ± 0.06 | 0.75 ± 0.06 | 6.11 ± 0.10 | 1.1 ± 0.1 | 6.40 ± 0.16 | 1.1 ± 0.1 | 8.29 ± 0.16 | 0.8 ± 0.1 |
Spiperone | 6 | 7.97 ± 0.11 | 0.74 ± 0.11 | 6.32 ± 0.13 | 0.7 ± 0.1 | 7.96 ± 0.24 | 1.0 ± 0.1 | 6.50 ± 0.08 | 0.9 ± 0.1 |
Prazosin | 6 | 9.86 ± 0.09 | 1.2 ± 0.20 | 9.34 ± 0.10 | 0.7 ± 0.1 | 9.16 ± 0.08 | 0.9 ± 0.05 | 9.69 ± 0.16 | 0.8 ± 0.0 |
Vohimbine | 4 | 7.00 ± 0.08 | 1.1 ± 0.15 | 6.09 ± 0.08 | 0.9 ± 0.04 | 5.54 ± 0.08 | 1.0 ± 0.05 | 6.18 ± 0.10 | 1.0 ± 0.0 |