Table 3

Comparison of alkaloid effects on MEPP decay constants

MLA14-DNBarbinineDeltaline
Controls
 Mean τ (ms ± S.D.)4.5  ± 1.43.5  ± 1.24.6  ± 0.64.0  ± 1.8
 No. of averaged MEPPs(14)(11)(20)(14)
[Alkaloid]0.10 μM0.05 μM0.50 μM20 μM
 Mean τ (ms ± S.D.)4.9  ± 2.43.1  ± 0.73.9  ± 0.7** 3.2  ± 0.9
 No. of averaged MEPPs(14)(17)(20)(12)
Rinse
 Mean τ (ms ± S.D.)7.7  ± 4.63-150 4.5  ± 0.96.3  ± 1.7*** 4.7  ± 2.8
 No. of averaged MEPPs(14)(12)(20)(14)

Each averaged MEPP is an average of 15 individual MEPPs for MLA; 11, 15, and 11 for 14-DN controls, treated and rinse, respectively; 10 for barbinine; and 14, 11, and 11 for deltaline controls, treated and rinse, respectively. Measurements of τ were made from a subset of MEPPs sampled from all of the animals (Table 2).

  • 3-150p < .05 greater than control. ** p < .01 less than control. *** p< .001 greater than control.